May 26 2010
Periodontal and Vascular diseases
Takehisa Iwai, MD, PhD, of the Tsukuba Vascular Center in Japan, published in the Journal of Periodontal Research Volume 44, Issue 6, Pages 689 – 694, 23 Oct 2009, important information related to Periodontal disease and it’s relationship to vascular disease.
Dr Iwai findings determined that “weak oral bacteria, such as periodontal bacteria, have been found in various vascular lesions, including atheroma, the thrombus of the occluded artery of Buerger’s disease, the abdominal aortic aneurismal wall and varicose veins. Serum titer levels of each bacterium are now available and have shown a significant relationship between severity and individual differences.”
His findings suggest that oral bacteria is related to vascular diseases and care should be taken to avoid oral bacteria from entering the month. He states, “it is estimated that lymph vessel openings trap bacteria en route from the mouth to the bloodstream and then carry them to the vein of the venous angle near the supraclavicular area. In the case of periodontal bacteria, a typical bacterium, such as Porphyromonasgingivalis, strongly activates platelets and makes them mass, including the bacteria without phagocytosis. Simultaneously, cytokines and serotonin are discharged. Platelet engulfment was clearly demonstrated by electron microscopy analysis. An animal study using rats showed the formation of a small arterial thrombus after continuous intravenous infusion of P. gingivalis for 2–4 wk.”
In conclusion his study determined that “weak oral bacteria, such as periodontal bacteria, may play an important role in the development of various vascular diseases, such as Buerger’s disease, atherosclerosis and varicose veins, through bacteremia.”
Dr. Anne A. Nicholas completed a post doctoral program in Periodontics & Dental Implants at Loma Linda University in 1992. Her practice, “The Palm Desert Center for Advanced Cosmetic and Implant Dentistry” is located at: 73-929 Larrea Street, Suite 2, Palm Desert, CA. Please feel free to stop by or call 760-340-1030 to schedule an exam. Dr. Nicholas offices provide dental services to Palm Desert, Palm Springs, Rancho Mirage, and the entire Coachella Valley.
Last year in the New York Times I recall an interesting article talking about the difference between implants and bridges. This article is a non-dental publication that gives an endorsement for implants as the new standard of care for missing teeth and its benefits for patients considering this option. Entitled “